Follow-up Algorithm (visit = FUP)
Figure: Follow-up algorithm
| ECR Criteria | HIV-1 RNA Criteria | HIV-1 DNA Criteria | Pass | Proposed Algorithm Result Summary |
|---|---|---|---|---|
| Non-reactive x 1 | Not detected | Not detected | 1 |
Blinded: No evidence of infection with HIV-1. Unblinded Report: No evidence of infection with HIV-1. If any previous HVTN HIV diagnostic test results showed evidence of vaccine-induced sero-reactivity, it is recommended that HIV diagnostic testing continue through the HVTN until no evidence of sero-reactivity is repeatedly demonstrated. |
| Reactive x1 | Not detected | Not detected | 1 |
Blinded: No evidence of infection with HIV-1. Unblinded: No evidence of infection with HIV-1. These results may be due to vaccine-induced sero-reactivity (VISR) or non-specific cross-reactivity. |
| Reactive x1 | Not detected | Positive | 1 |
Blinded or Unblinded: HIV-1 Infected based on FUP and SRV or CFM lab results. |
| Reactive x1 | Positive | Positive | 1 |
Blinded or Unblinded: HIV-1 Infected based on FUP and SRV or CFM lab results. |